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KMID : 0903520000430040303
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Journal of the Korean Society of Agricultural Chemistry and Biotechnology
2000 Volume.43 No. 4 p.303 ~ p.308
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Effect of Water - Extracted of Leaves from Morus alba and Cudrania tricuspidata on the Lipid Concentrations of Serum and Liver in Rats
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Abstract
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Male Sprague-Dawley rats received either a cholesterol diet (Control group) or cholesterol diets supplemented with the water-extracted of leaves from Morus alba (MA group) or Cudrania tricuspidata (CT group) at the level of 1% for 2 weeks. The concentration of serum triglyceride was significantly lower in the CT group and was also lower in the MA group than in the control group. The liver cholesterol concentration was significantly lower in the MA group than in the control group, but not significantly different between the CT group and the control group. The concentration of phospholipid in serum was an increasing tendency in the MA group and was a decreasing tendency in the CT group compared to that in the control group. Body weight gain, food intake, food efficiency, the concentrations of triglyceride and phospholipid in liver, and the total cholesterol, HDL-cholesterol and glucose in serum were not significantly different among dietary groups. These results suggest that the water-extracted from leaves of Morus alba and Cudrania tricuspidata exerts a hypotriglycerolemic effect in the cholesterol-fed rats.
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